RCMI International Symposium on Health Disparities
November 12-15, 2000
San Juan, Puerto Rico

WORKSHOP

EMERGING TECHNOLOGIES:
MULTIPLEXING MICROSPHERE ARRAYS
Monday, November 13, 2000
1:30 p.m. - 4:00 p.m.

Synergistic Multi-Analyte Profiling Using
Suspension Array Technology

Francis Mandy
National Laboratory for Analytical Cytology
Bureau of HIV/AIDS/STD/TB
Laboratory Centre for Disease Control
Health Protection Branch Health Canada
Ottawa, Ontario Canada

The development of multi-parameter flow analysis, as it relates to immunophenotyping, has provided the opportunity to exploit cytological technologies for numerous applications. The future potential of this technology lies in its unique capacity for quantitative measurement of molecular interactions in solid phase conditions, yet they approximate classical liquid phase kinetics. One future option is an instrument system that has the capacity to analyze microsphere-based assays. Can flow cytometry based technology progress fast enough to meet the requirements of diagnostic medicine of the next decade? This workshop willprovide you with some insights and possible directions for implemetation of this fast developing technology.

Genomic Analysis Using Multiplexing Microsphere Arrays

John Nolan, Ph.D.
National Flow Cytometry Resource
Los Alamos National Laboratory
Los Alamos, New Mexico

The completion of the Human Genome Project offers enormous potential for stimulating biomedical breakthroughs, but this potential will only be realized if technologies for rapid and cost-efficient genomic analysis are available. Genomic analysis using multiplexing microsphere arrays offers a unique combination of parallel analysis and throughput, and is being applied to a number of basic and clinical research problems.