RCMI International Symposium on Health Disparities
November 12-15, 2000
San Juan, Puerto Rico

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WORKSHOP

DNA Based Diagnosis and Monitoring of Diseases
Tuesday, November 14, 2000
1:30 p.m. - 4:30 p.m.

CONTENT

Introduction
Yasuhiro Yamamura, Ph.D.
Ponce School of Medicine

Amplifying the Power of Clinical and Research Medicine
Maurice Rosenstraus, Ph.D.
Roche Molecular Systems

LiPA (Line Probe Assay) Technology:
Post PCR Applications in Infectious Diseases

Brian Brody, Ph.D.
Innogenetics

DNA technology has become an essential part of modern day diagnosis and disease monitoring. Not only pathogens can be identified and quantified, host gene expression during disease progression may be monitored. For examples, certain host genes influence the behavior of neoplasia or their responses to therapy; qualitative or quantitative assessment of viral genes, e.g., HIV, HCV, HSV, HPV, etc., are used for specific diagnosis of infection and in certain cases for monitoring viral responses to therapeutic agents. Such information can be effectively utilized to maximize the effectiveness of available therapeutic regimens or selection of effective drugs. This workshop addresses three major emerging areas of cutting edge technology which have immediate clinical applications: microarray technology, real-time PCR and line probe assay. Basic concept of the technologies and examples of their applications for different disease management will be addressed by leading scientists of the fields. A tropical fruit bar will be offered during the workshop.